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Testing for blister packaging

Views:0     Author:Site Editor     Publish Time: 2021-10-16      Origin:Site

Testing requirements for blister packaging

The main packaging object of blister packaging is solid drugs, and the package should be isolated from the outside world, on the one hand, to prevent the volatilization, escape and leakage of drug active ingredients. Volatile pharmaceutical ingredients can dissolve in the inside of packaging materials and spread to the other side under osmotic pressure. For example, solid pharmaceutical preparations containing aromatic ingredients and volatile active ingredients are volatile and penetrate certain materials.

On the other hand, prevent the outside air, water, foreign bodies, microorganisms into contact with drugs. Air contains oxygen, moisture, a large number of microorganisms and foreign matter particles, which will lead to oxidation, hydrolysis, degradation, pollution and fermentation of the drug after entering the package.

PTP aluminum foil and PVC hard sheet or PVC/PVDC composite hard sheet used in bubble cover packaging will directly contact with drugs, so special attention should be paid to the detection of materials, detection items include appearance, insidities, tensile strength, impact strength, thermal shrinkage and other mechanical properties, as well as health indicators, etc. There are corresponding testing methods and standards (or enterprise standards) respectively.

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