Current situation of tablet press The tablet press is the manufacturing equipment in the history of China's production. Tablet press specifications, quantity, is a long-term export, mass production of pharmaceutical equipment. According to statistics, there are nearly 50 manufacturers in China, with an annual output of 3000 units/year and more than 70 units of product specifications, it can be executed by pressing round chips, rigid chips, profiled chips, double chips, multi-layer chips, ring chips, chip bags and so on. It is an indisputable fact that the quantity, variety, specification and output of compact-core manufacturing rank first in the world. In recent years, enterprises that have formed "filmmaking mechanism" begin to pay attention to product quality and believe in the business philosophy of winning by quality. According to the characteristics of domestic pharmaceutical enterprises, the variety of drugs is large and the production scale is small. After the techno

Composition of capsule Capsules are mainly composed of hollow capsules and fillers. 1. Hollow capsule Gelatin is the main raw material for making hollow capsules. Necessary additives must be added to ensure its quality. Excipients include sodium plasticizer such as glycerin to increase the toughness and elasticity of the capsule; Sodium carboxymethyl cellulose increases the viscosity and plasticity of gelatin liquid; Thickeners, such as AGAR, increase the setting power of liquid glue; Similar to 2-3% titanium dioxide, light prevents drug oxidation; Tartrazine, carmine, etc., add aesthetics, easy to recognize; Preservatives, such as master gold, provide the protection of liquid glue in the preparation of capsule molds; Aroma mild, vanilla, delicate taste, as ethyl 0.1% adjustment. 2. Filling technology Drugs are obtained by adding appropriate additives such as diluents, fluxes, disinfectants, etc. A uniform powder, particle, or patch After filling ordinary pellets, quick release,

Blister wrapped aluminum foil PTP aluminum foil can be divided into tactile aluminum foil, peeled aluminum foil and peeled aluminum foil according to the use; Aluminum foil materials are divided into rigid aluminum foil, flexible aluminum foil and composite materials. The characteristics of aluminum foil can be divided into preventing forgery, protecting children's safety, protecting children's safety and the comfort of the elderly, special protection aluminum foil, etc. Aluminum contact rupture: aluminum plating more extensive, may not be easy, can be soft, the general thickness of 15 meters to 30 meters, its basic structure and hot ball aluminum/said, PVC, PP(polypropylene) polystyrene, polyester (PET), (), PE(polyethylene) and other composite materials and sealed cover, good air tightness. Strip aluminum foil: Flat and flat aluminum foil is basically impervious to air, such as aluminum foil error is large, contact with different thermal seal resistance and matrix is not

The principle of the tablet press Dose control. Different tablets require different dosages. For large dosage adjustment, different punching diameters are selected, such as 5mm, 8mm, 11mm and 12mm. After the mold size is determined, a very small dose can be adjusted by adjusting the depth of the hole, extending the hole to the hollow, changing the length of the middle hole on the back of the cover, and adjusting the charge amount. Therefore, there must be a mechanism in the press to adjust the original position of the pressure hole so that it is crushed under modulation to meet the requirements of the dosing. However, this arrangement system is critical because different powder samples are different. The way substances move can also make a big difference in controlling doses, such as when drug particles are driven by confidence and fall into tuberculosis during the weak process. When stress enters an environment multiple times, more drugs are added, making the environment more compac

Advantages of blister packaging Aluminum foil blister packaging, also known as blister packaging, is a new type of solid packaging. After the plastic has hardened, the plastic, tablets, capsules and dense medicine are first put into the hole, and then glued together with hot aluminum foil to form a separate sealed package. At present, there are a lot of solid drugs are packaged with glass, although can avoid light, moistureproof, anti-oxidation, but the packaging capacity is large, technical content is not high. For wonder drugs, this traditional form of packaging failed to protect against moisture and mold, which led to the rapid withdrawal of large bottles of brown glass from the market in recent years. Compared with bottled drugs, the advantages of foam packaging are easy to realize, which can reduce pollution and drug abuse leading to obvious advantages in the process of implementation in gas and foam packaging, prevention, waterproofing, health and safety, production effic

Abnormal condition of the capsule filling machine Automatic capsule filling machine is a kind of touch screen operation, variable frequency speed regulation, sensitive action, accurate measurement, novel filling structure, beautiful appearance, easy to operate, can realize automatic bag changing, sorting and capsule filling, thereby reducing labor intensity and improving production efficiency. However, there may be some anomalies in the operation: 1. The capsule and shell cannot be separated. For the capsule's own reasons, replace the appropriate capsule. The vacuum is too small. The vacuum is too small for several reasons. If it is a vacuum pump, have it repaired or replaced by a mechanic. The vacuum pump connected to the isolation chamber failed and the piping was replaced. The filter film of vacuum pump should be blocked and cleaned. Or maybe the water level is too low and we'll have to replace a bigger pipe. Of course, we have to look at the situation and find o

Powder for tablet press 2 1. Compressible starch: also known as glutinous starch (glutinous starch), is a new type of medical excipients, has been obtained in the United Kingdom, the United States, Japan and China pharmacopoeic collection, China was successfully developed in 1988, now there is a large number of the market of glutinous starch. Domestic printed starch is partially pregelatinized starch (completely pregelatinized starch also known as alpha starch) starch, is foreign toner can not be compared. It is a kind of multifunctional auxiliary material which can be used as filler. It has good fluidity, pressure resistance, self-lubricity and drying adhesion, and good disinfection effect. In direct extrusion powder, magnesium stearate dosage should not exceed 0.5%, so as not to produce softening effect. 2.Cellulose (ACyl MCC), a kind of partially hydrolyzed crystalline cellulose and cellulose, can be pressed into solid egg powder. Cellulose (ACyl MCC), which is made of higher hard

The use of capsule filling machine 1. Press the green button on the "power switch" and the power will start. 2. Adjust the "Strong and weak adjustment button" and rotate clockwise. At the moment, the processing plate, which holds the "vibratory struts" together, begins to vibrate, and the touch of the hand on the processing plate is adjusted to feel the specific intensity of the oscillation. 3. Package the capsules in powder form. The capsules are put into "powder cartridges", each containing about 300 particles. Place the capsule LIDS into the "finished capsule LIDS," each containing about 300 capsules. It is made of plexiglass with a large round funnel on the glass and a small funnel hole at the bottom, the diameter of which is the same as that of the capsule. 4.After about 30 seconds, after filling the capsule and closing the lid, land in a round hole and open and open again. If someone opens the bottom, lift the capsule by gently pressing on the lid. 5. Horizontal

Application of blister packaging machine Blister packaging machine is also known as blow molding packaging machine, it USES plastic film or foam sheet, and heat seal, cut, etc. The blister regulator is mainly blister machine and heat seal machine. Usually used in the medical food packaging industry, the size and shape of bubble shells, vacuoles and bubble boxes used for packaging blister hoods vary with the shape of the packaging items; In addition, there are many types of blister packaging machines and various blister packaging methods. The basic principles of packaging bubble shape, the process is as follows: in view of its importance relative to the production of drug packaging relatively fixed, health and safety, so it should be automatic filling line, from the production automation process to complete, can also print leaflets, cartons, etc. Combine the supply chain process with the automatic packaging of packaging materials. (1) Unfold the plastic sheet and move forward;

The powder of the tablet press Common fillers include starch, sugar, cellulose and inorganic salts; Under pressure tablet diameter of 6 mm, it is usually difficult to exceed 100 mg. If the primary medication is under several milligrams or several tens of milligrams, without the added component, the thinner is not under tablet formation. Therefore, the pressure pill is under pressure. Starch: Compared to corn starch, its environment is very stable, most drugs don't work, its price is low, its humidity is low, and its color is small. In real life, starch can be pressed very low, often mixed with other powder molding. Powdered sugar is asparagus sucrose crystal powder without cold after drying, crushing white powder has the advantages of medicine can increase the hardness of coking coal have been trunk and the steps of the tablet surface gloss z handsome, defect is good water imbibition, long-term preservation, excessive hardness and disintegration, opium and dissolves cleanin