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Capsules filling and quality inspection

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Capsules filling and quality inspection

Prepare empty capsules with contents

The empty capsule is divided into two sections, called cap and body respectively. Empty capsules can be divided into three types: colorless transparent, colored transparent and opaque according to whether they have color or not. According to the type of lock, it is divided into two types: ordinary type and lock type. According to the size, it can be divided into eight kinds of size: 000, 00, 0, 1, 2, 3, 4 and 5, among which the largest size is 000 and the smallest size is 5.

Contents can be prepared into different forms according to drug properties and clinical needs, mainly in the form of powder, pellet and pellet.

Fill the empty capsule

Mass production can be fully automatic capsule filling machine or semi-automatic capsule filling agent to fill drugs, drugs filled with capsule polishing machine to remove the adsorption on the outer wall of the capsule fine powder, so that the capsule clean.

A small amount of trial production can be used for capsule filling plate or manual medicine filling, the filled capsule is wrapped with clean gauze, gently rub and roll to make the capsule bright.

Quality inspection

The filling capsules were tested for content determination, disintegration time limit, filling volume difference, moisture content, microbial limit and other items. Check method for the difference of capsule volume; Take 20 test samples, weigh them accurately, pour out the contents, and wipe the hard capsules with a small brush or other appropriate tools; Then accurately weigh the weight of the capsule and calculate the content and average content of each grain. According to the regulations, no more than 2 granules shall be dried if the difference limit of filling quantity is exceeded, and no one granules shall exceed the limit by 1 times.

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