• Product Name
  • Product Keyword
  • Product Model
  • Product Summary
  • Product Description
  • Multi Field Search
News Room
You are here: Home » News Room » PRODUCTS NEWS » The problems and methods of the tablet press

The problems and methods of the tablet press

Views:0     Author:Site Editor     Publish Time: 2020-10-20      Origin:Site

The problems and methods of the tablet press

The disintegration delay in the tablet pressing process may occur in the tablet pressing machine, which means the disintegration time exceeds the pharmacopoeia.

Reasons for disintegrating delay: insufficient amount of disintegrating agent; high viscosity of adhesive; high amount of hydrophobic lubricant; high pressure; high hardness of tablet.

Solution: choose good disintegrating agent, or increase the dosage, reduce the adhesive dosage, or replace the adhesive with small viscosity, add hydrophilic lubricant, adjust the pressure of the tablet press.

Reasons for the big difference in weight: particle size, flow rate, not flexible down and rise, too much or too little charge.

Solution: re-granulation, add flow AIDS, stop check, adjust the hopper to make the same amount of packing.

Discoloration or spot refers to the change of hydrochloric acid on the surface of the tablet or the appearance of different color spots, pitting.

The reason is that the particles are too hard, the mixture is uneven, and there are stains on the machine.

Refers to the surface of the tablet of hydrochloric acid change or the appearance of different color spots, pitting, shadows

Solution: Re-granulate, mix well and scrub the machine.

Causes of unqualified uniformity and degree: uneven mixing, more fine powder, uneven particle size, poor fluidity, migration of soluble components.

Solution: Re-granulate, mix well, and improve the drying process.

压片

  info@hanyoo.net
  0086 25 5621 6295
  0086 25 5621 6289
  0086 187 5183 8183
  No. 380 Sanqiaogeng, Gaochun District,
Nanjing, China. 211300

Quick Link

QR Code

Capsule Filling Machine, Blister Packing Machine
Copyright  2016 Jiangsu Hanyoo Pharmatech Co., Ltd. All rights reserved. Capsule Filling Machine, Blister Packing Machine, Cartoning Machine Professional Manufacture.