Discussion on blister packaging Blister packaging is a method of packaging in which the product is sealed between a blister formed by transparent plastic sheets and a base plate (made of cardboard, plastic film or sheet, aluminum foil or their composite materials). Because this packing method is based on the substrate, so also known as the substrate packaging turbulence. Blister packaging made of packaging, on the one hand has a transparent appearance, you can clearly see the appearance of the product; At the same time on the substrate can be printed exquisite patterns and commodity instructions, easy to display and use. On the other hand, the packaged product is fixed between the forming bubble cover and the substrate, which is not easy to be damaged in transportation and sales. It can not only protect the product, prolong the storage period, but also play the role of promoting products and expanding sales. Blister packaging was originally used for drug packaging. Now in addition t

Blister packaging material adhesive Blister packaging is the main packaging form of solid dosage form of health food and medicine in China. Among them, the medicinal aluminum foil is pure industrial aluminum foil as the base material, on the surface of the printed word pattern and coated with protective agent, and on the other side coated with adhesive. The purpose of coating protective agent is to prevent the surface printing ink layer wear, but also to prevent aluminum foil winding, outer ink and inner adhesive contact caused by drug contamination. The purpose of the adhesive is to bond the aluminum foil to the plastic sheet, so that the drug is sealed. Currently used adhesives are mainly divided into single component glue and two component glue. The components of single component glue are mainly natural rubber and nitrocellulose fiber, acrylate fees, because the main agent is an elastomer, coupled with adhesives as additives, with organic solvents into emulsion, it has dry, hot mel

Blister packaging barrier testing At present, the overall barrier detection technology of packaging has been mature, but because the overall size of the bubble cover is very small, it is difficult to use general packaging overall detection accessories, and the strength of its aluminum foil layer is weaker than plastic, so the overall barrier detection technology has not been applied in the bubble cover packaging. However, in fact, due to the uniformity of the material adhesive coating amount, the heating and stretching rate of the material and the mechanical strength of aluminum foil, the oxygen and water vapor permeability of the actual bubble cover are higher than the calculated values based on the membrane sun barrier data. We have tested some drugs in the market using bubble cover package, and compared the actual barrier data of aluminum foil and PVC hard sheet or PVC/PVDC composite hard sheet obtained from some manufacturers, we found that although the barrier test data of packag

Advantages and disadvantages of blister packaging Blister packaging is one of the most widely used and fastest developing flexible packaging materials in pharmaceutical industry, and also the main packaging form of solid drug dosage form in China. It has strong gas sealing, excellent moisture resistance, good oil resistance, drug resistance and solvent resistance, excellent resistance to oxygen, water vapor, carbon dioxide gas in the air, can meet the special requirements of drug bubble packaging. The use of aluminum foil as the substrate, the surface should be clean and shiny, good printing suitability, can be firmly coated with heat sealing coating, to ensure that the melt of the heat sealing coating, the substrate and bubble cover can be closely combined. Aluminum foil is non-toxic, tasteless, has excellent electrical conductivity and shading, has high moisture resistance, gas resistance and taste protection, can most effectively protect the packaged drugs, is a kind of packaging

Drug blister packaging trends 1) Completely effective protection of drugs. As with any form of packaging, the protection and effectiveness of drugs are still the basic requirements of blister packaging. 2) Safety and convenience of medication. Develop safe packaging for children and convenient packaging for the elderly. 3) Unique anti-counterfeiting packaging. Using the new technology to realize the diversified anti-counterfeiting of bubble cover packaging materials, can not only reflect the individuation of drug packaging, but also protect the products and brands of enterprises. 4) "green" environmental protection packaging. Vigorously develop and popularize new environment-friendly blister packaging materials that can be recycled, degradable and return to nature, and do not pollute the atmosphere by burning, so as to fundamentally solve the "white pollution" in drug packaging. 5) Serialized packaging. With the implementation of OTC in China's pharmaceutical industry, more and mo

Testing requirements for blister packaging The main packaging object of blister packaging is solid drugs, and the package should be isolated from the outside world, on the one hand, to prevent the volatilization, escape and leakage of drug active ingredients. Volatile pharmaceutical ingredients can dissolve in the inside of packaging materials and spread to the other side under osmotic pressure. For example, solid pharmaceutical preparations containing aromatic ingredients and volatile active ingredients are volatile and penetrate certain materials. On the other hand, prevent the outside air, water, foreign bodies, microorganisms into contact with drugs. Air contains oxygen, moisture, a large number of microorganisms and foreign matter particles, which will lead to oxidation, hydrolysis, degradation, pollution and fermentation of the drug after entering the package. PTP aluminum foil and PVC hard sheet or PVC/PVDC composite hard sheet used in bubble cover packaging will directly con

Blister packaging of milk tablets Milk tablet, as a deep processed product of milk, is made of milk powder, plant milk powder, whey protein powder, sucrose and so on. It is a nutritious instant snack. At present, 90% of milk tablets are packaged with a flat blister package, which plays an important role in storage and transportation. Flat blister Packaging, also known as Press Through Packaging (PTP), is to fill the contents into the blister through vacuum vacuuming (blowing) or molding, and heat seal the lid materials such as aluminum foil with the base material under a certain pressure, temperature and time. The main body of the lid material is 99% electrolytic aluminum foil made by calendering, which is the most used metal material in packaging. It is non-toxic and tasteless, and has excellent moisture-proof, gas resistance, taste retention and light shading, which can most effectively protect the quality of the contents. After single-side printing, the surface of aluminum foil is

Initial use of blister packaging Blister packaging The original blister packaging is mainly used for drug packaging. At that time, the company was trying to overcome its disadvantages such as inconvenient use of bottles such as glass and plastic bottles and large investment in packaging production lines. In addition, the demand for dose packaging and small tablet packaging is increasing, so bubble packaging appeared in the 1950s and has been widely used. Later, through in-depth research and continuous improvement of blister packaging materials, technology and machinery, great progress has been made in packaging quality, speed and economy. Now in addition to drug tablets, capsules and suppositories and other packaging, food and daily necessities and other products are also widely used in packaging. If the use of automatic packaging machine, but also improve production efficiency. Reduce costs. Blister package of a medicine: it can protect the product from moisture, dust, pollution, th

Indentation and cutting requirements for blister packaging China's laws have made more and more strict restrictions on product packaging, and put forward higher requirements for labeling and printing on packaging. It is clearly required in the industry standard of pharmaceutical blister packaging machine that the packaging machine must have batch number device. Packaging machine printing generally adopts punch molding method to print the production date and batch number. Batch number can be carried out in a separate station, also can be with heat sealing, indentation at the same station. Indentation An aluminum-plastic package of drugs may be suitable for multiple doses. For ease of use, easily cracked marks can be stamped on a piece and the tablet can be easily broken into several small pieces by hand. Each small piece can be used for a single dose. Blanking will be sealed after the strip packaging product blanking into the specified size (that is, a piece of size) known as blankin

The use of blister packaging Blister packaging The original blister packaging is mainly used for drug packaging. At that time, in order to overcome the disadvantages of inconvenient use of glass bottles, plastic bottles and other bottled drugs, large investment in packaging production line, coupled with the increasing demand for dose packaging, small pill packaging, bubble packaging appeared in the 1950s and has been widely used. Later, through the in-depth study and continuous improvement of blister packaging materials, technology and machinery, it has made great progress in packaging quality, speed and economy. Now in addition to drug tablets, capsules and suppositories and other packaging, food and daily necessities and other products are also widely used in packaging. If the use of automatic packaging machine, but also improve production efficiency, reduce costs. A blister package for a drug, which can protect the product from moisture, dust, pollution, theft and damage, prolong