Blister packaging material development direction

Blister packaging material development direction

Because drugs are very sensitive to moisture, moisture and light permeability, as the basic material used in drug blister packaging, blister material is required to effectively protect drugs and meet the requirements of advanced packaging technology. China's pharmaceutical packaging blister material production after many years of rapid development, indeed has a great improvement, for China's pharmaceutical packaging has made an indelible contribution. But there are still many aspects which cannot be ignored and need to be developed vigorously.

1) Develop high barrier materials. Polyvinyl chloride (PVC) is a foaming material that is still widely used in China, but the barrier of PVC is not ideal, and it will have a certain impact on the human body and the environment. Therefore, polyvinylidene chloride (PVDC) and its composites with excellent barrier properties, and cyclic olefin copolymer (COC) and its composites with excellent moisture resistance and thermoforming properties should be developed as soon as possible.

2) Develop environment-friendly materials. In order to realize "green" blister packaging, it is necessary to develop and popularize non-toxic blister materials, such as polyethylene (PE), polypropylene (PP) and their composite materials, which can be degraded and recycled, and do not pollute the environment.

3) Develop materials suitable for "antibacterial" packaging. Although the clean environment of pharmaceutical production is designed in accordance with GMP requirements, the production and packaging process of any dosage form is not necessarily sterile. Therefore, the development of antibacterial polymer materials used in blister packaging, in order to inhibit bacterial pollution, prolong the shelf life of drugs, this will also become one of the directions of blister packaging development.

4) Develop nano-packaging materials. The application of nanotechnology in the field of medicine to develop materials such as nano-paper, polymer-based nanocomposites (PNMC), nano-adhesive and so on will open up a new field for drug blipper packaging.

5) Develop safe, hygienic and non-toxic materials. Drug packaging blister materials are in direct contact with drugs, so the development of blister materials that do not release particles, react with and adhere to drugs during packaging and long-term storage should be strengthened, such as trifluorovinyl chloride homopolymer (ACLAR) composites that do not melt or adhere to molds, etc.