Dose control of tablet press

Dose control of tablet press

Different tablets have different dose requirements, and large dose adjustment is achieved by selecting different punch diameters of the die. After selecting the size of the die, the small dose adjustment is to change the actual length of the die hole after the back cover by adjusting the depth of the down punch into the die hole, so as to achieve the purpose of adjusting the filling volume of the drug in the die hole. Therefore, the tablet press should have a mechanism to adjust the original position of the punch in the die hole to meet the requirements of dose regulation.

Control tablet thickness and degree of compaction

The dosage of the drug is determined according to the prescription and pharmacopoeia and cannot be changed. Dosage pressure is also required for storage, storage and disintegration, which will affect the actual thickness and appearance of the tablet. Pressure regulation during tablet pressing is essential. This is achieved by adjusting the downward flow of the top punch through the die hole. Some tablet press not only has up and down action in the process of tablet pressing, but also can have down and up action, from up and down relative movement to complete the tablet pressing process. But the pressure regulation is mainly realized by adjusting the upward and downward flow of the billion structure of pressure regulation and control.