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Powder running improvement of tablet press In the process of tablet production, tablet pressing is the process of forming the material. Tablet pressing process can be briefly summarized as follows: the powder material from the hopper into the forced feeding mechanism; The cloth impeller of the forced feeding mechanism will cloth the material into the middle plate (also known as the main rotary table) in the die hole; Upper and lower punch with the central disk rotating at the same time, by the upper and lower guide rail curve groove, a smooth curve and exercise, after filling, preloading, main pressure, the four stations, after scraping powder area, preloading area, the main pressure zone, the area, remaining material recycling cleaning area, form a circle, the material crushing and continuous tablet is the cycle of repeated. At present, the key components of the domestic high-speed tablet press, such as the hopper, the forced feeding mechanism, the middle plate, etc., are indepe
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Blister packing machine shutdown protection Some advanced aluminum-plastic blister packing machines are equipped with various automatic monitoring devices, which can play a variety of protective roles and automatically stop the operation of the machine when the following problems are found: (1) The safety cover is open; (2) the compressed air pressure is insufficient; (3) the heating temperature is not enough; (4) P V C film or aluminum foil used up; (5) The packaged drugs are used up; (6) mechanical overload at some stations; (7) Circuit overload.
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The mechanism of semi-automatic capsule filling machine Used for capsule filling, seeding, powder filling and locking automatically, instead of manual filling, reduce labor intensity, improve production efficiency, domestic or imported mechanism capsule can be used, the filling dose is accurate. It adopts electric and pneumatic joint control, equipped with electronic automatic counting device and computer speed regulating device, and completes the actions of capsule positioning, separation, filling and locking respectively. Adopt three stepless speed regulating motor to drive operation, easy to maintain and operate. The vacuum pump is started and stopped by button instruction, interlocked with AC contactor, equipped with vacuum gauge, throttle valve, display and regulation system pressure. The seeding mechanism is powered by a single stepless variable speed motor. The display of seeding speed automatically runs for one week. The machine is set by a counter (60 times) to
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Fatigue fracture of pressing die of tablet press The punching die of the tablet press is a part of repeated motion, so the probability of fatigue fracture exists. Once the die breaks in the work, the consequence is very serious. Therefore, the fatigue fracture of the die should be strictly prevented. We know that the fatigue fracture of steel has a development process of crack formation, expansion and fracture, and the fatigue fracture formation stage generally accounts for 70%~80% of the fatigue life. Therefore, preventing the premature formation of fatigue crack is the key to improve fatigue fracture. Fatigue fracture is the part under the action of cyclic load, starting from some weak links, the weak links of the punching die is in the punch arc transition which is easy to produce stress concentration, to prevent the formation of fatigue crack, the first is the selection of the punching die, that is, the punch and the punch body of the arc can not be too small; Secondly, the r
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The performance of flat type blister packing machine 1, With heating plate temperature control detection, main motor overload protection, PVC and PTP package material level detection. 2, mechanical friction wheel deceleration, speed control, better than the constant ratio of mechanical reducer speed and transmission. 3, the use of four mold box box with (spline) shaft drive, improve the transmission rigidity and work to maintain synchronization. 4, the overall use of open layout structure, good visibility, machine maintenance, adjustment is simple and convenient. 5. Adopt modular mold, easy to replace, install and adjust. The same machine multi-specification production, low mold cost. 6, Adopt PLC microcomputer control, touch screen operation, Chinese and digital display, fault diagnosis Chinese prompt, simple and reliable operation, easy maintenance.
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Flowability of capsule filling material The fluidity of filling material also refers to the smoothness. The variety of filling material is often powder and granule, etc. The fluidity of filling material will directly affect the control of capsule loading accuracy. The Angle of recline, bulk density, particle size distribution and water content of powder or granule have direct influence on its fluidity. Generally speaking, when the filling powder or granules are piled up, the Angle of recline of granules is smaller than that of powder, so the flow of granules is good, and the filling precision of capsule filling is easy to control. Bulk density refers to the weight per unit volume of powder or granule. In the process of filling, the weight per unit volume is larger, and the fluidity is good. It is also easy to control the accuracy of capsule filling. On the contrary, the weight per unit volume is small, the fluidity is poor, and it is difficult to control the accuracy of capsule f
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Tablet press selection basis According to the production process and quality requirements of drugs, the selection of tablet press is mainly from the following aspects: (1) According to the characteristics of powder and particle, choose the appropriate tablet press (mainly Chinese medicine or western medicine, the composition proportion of raw and auxiliary materials, etc.); (2) Determine the output of equipment according to capacity and reserved capacity; (3) select the appropriate charging system according to the existing process; (4) According to the production record and deviation, equipment maintenance frequency and equipment control points in the production process of the product in the past; (5) the operation is convenient, reliable, there is a necessary adjustment device. Such as mechanical regulating device, filling regulating device, pressure regulating device, speed regulating device, sheet thickness regulating device, etc. (6) The design of the tablet pr
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Typing problem of blister packing machine Type individual font is not clear can use a wire brush to clean the font surface debris, change the font, or on the pressure plate on the heat insulation film or medical tape. If the type is not clear, adjust the preload bolt, but do not increase too much preload, otherwise the noise is very large and easy to fatigue damage, in the case of preload can not be increased, you can appropriately increase the temperature of 5-10 degrees. Typing position adjustment can realize the up and down position of the font by adjusting the up and down moving handle, while moving the typing bar to change the left and right position of the font.
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The function of each structure of the tablet press The lower punch fastening ring is unified, which has the following functions There is no need to adjust the fixed ring of each punch separately. The punch replacement speed is fast and the parts need to be cleaned less. This structure makes the fastening resistance of each punch equal, no need to adjust again. Special sealing structure The window is sealed by the special dismountable structure and material for cleaning, which ensures that the machine pressing studio is completely sealed and the cross contamination caused by dust is eliminated. The screw hole of the punching table is closed, and the sealing ring covers the screw hole of the punching table, so as to prevent the powder from entering, and accordingly reduce the cleaning time. Working window frame structure in line with GMP requirements The four-sided window structure is composed of frameless double vacuum, the surface is smooth and easy to clean, and the st
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Capsule filling machine load test Load test can be carried out after passing no-load test. Manually run the device, open the capsule holder, and allow the capsule to drain into the capsule plate hole. And adjust the push pawl, pressure pawl and capsule directional seat of the pawl mechanism as appropriate, so that it is on the center. The capsule should be discharged into the hole of the capsule plate smoothly, and the action of the plucking cap, pressing and pushing mechanism is coordinated. The charging powder should run for no less than 1 hour, check the metering device, and adjust it flexible. The difference in the loading accuracy of the powder should not be more than 5%, and it should comply with the provisions of the Chinese Pharmacopoeia. The qualified rate of empty bag row, dial cap and closure is above 99%. The qualified rate of finished products shall not be less than 99.7%. Electrical control is sensitive and reliable. Vacuum can be adjusted freely.