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Application of blister packaging in pharmaceutical industry Medicine is a necessity of life, and pharmaceutical packaging is an important part of the packaging industry. The global pharmaceutical industry likes to use high transparency packaging and fixed dose packaging, pharmaceutical packaging design began to pay attention to human care and children's safety, can reduce patients taking mistakes. Among many packaging containers, blister packaging has the most potential for development. Blister packaging has the advantages of strong barrier, beautiful appearance, long shelf life, easy to use and so on. In addition, plastic bottles remain the most widely used pharmaceutical packaging container, accounting for a large share of the pharmaceutical packaging market demand, especially in Latin America, Eastern Europe and the developing Asia-Pacific region are growing at a rapid rate. At present, the plastic packaging of medicine in China accounts for about 1/3 of the total packaging materia
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Configuration of blister packing machine 1, molding, heat sealing, batch number, indentation, blanking and other devices all adopt the rack-made mandlet positioning, shake the handle, all kinds of devices can easily move on the heart shaft, the machine is equipped with a ruler, convenient correction, rapid and accurate positioning. 2, manipulator traction, the use of double pendulum rod device, increase the adjustable range of traction stroke, can adapt to the packaging of various sizes of drug version. The machine to plate heating, positive pressure molding, upper and lower mesh, cylinder heat sealing, automatic feeding, automatic indentation, batch number, automatic blanking plate, simple operation and reliable operation. 3, the positive pressure air molding with the configuration of mechanical punch, to ensure that the bubble cap forming uniform crisp, suitable for large size or special shape of the packing of pills, medical equipment; Equipped with special automatic feeder, it c
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Packing advantages of blister packing machine The blistering packaging of drugs is to fill the groove with tablets, pills, capsules and other solid drugs after the transparent plastic hard sheet is blistered, and then heat the aluminum foil coated with adhesive to bond together, forming an independent sealing package. Blister packaging has great advantages: firstly, it provides the patients with a single dose of medicine packaging, which is convenient and economical; Secondly, blistor packaging has the advantages of good performance, high production efficiency, low cost, small storage space, light weight and convenient transportation. Moreover, the safety is good, because the blister packaging can be printed with text, the hair and the drug can avoid the wrong drug phenomenon. Pharmaceutical blister packaging on the market at present is mainly PVC base material, PVC base material is made from PVC resin add certain processing AIDS, produced by the method of extrusion, rolling processi
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Blister packaging machine molding mode There are two ways of bubble cap forming, namely pressure molding and blister molding. Compression molding is to use compressed air to blow the softening sheet to the mold, so that it is close to the four walls of the mold. The mold adopts flat shape, generally for intermittent transmission, can also be used for continuous transmission, its molding quality is good, suitable for both deep and shallow bubble cover. In blister molding, the softening sheet is adsorbed on the four walls of the mold by means of vacuumizing to form holes in the bubble cap. The shape of the cylinder is mainly used for continuous transmission. Due to the limited suction generated by vacuum and the limited Angle of the bubble cap from the cylinder after forming, the mold is only suitable for shallow bubble cap and thin materials. Blister packaging machine according to the degree of automation, there are semi-automatic packaging machine, automatic packaging machine and au
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Technology of aluminum - plastic bubble cap packing machine Film conveying blister packaging machine is a multi-functional packaging machine, each packaging process is carried out in different stations. The packing machine is provided with a number of film conveying mechanisms, whose function is to transport the film and make it through each station, to complete the blister packaging process. Various types of domestic blistering packaging machine used in the conveying mechanism of groove wheel mechanism, CAM rocker mechanism, CAM indexing mechanism, ratchet mechanism, etc., can be selected according to the accuracy of the conveying position, acceleration curve and the adaptability of packaging materials. Heating The forming film is heated to a temperature at which it can be thermoformed, depending on the packaging material chosen. For hard PVC, the easier molding temperature range is 110 ~ 130℃. This range of PVC film has sufficient thermal strength and elongation. The temperature ha
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Application of servo in blister packing machine (1) PLC pulse function is not strong. In many large or medium-sized PLC in order to improve the PLC operation speed, the high speed pulse output function modularization. There is often no high-speed pulse output on THE PLC CPU module. The servo has intelligent function, which can drive the motor without external pulse. (2) During the operation of the equipment, there is a period of high speed pulse output by PLC due to the start of some interference sources, which makes the servo in the original system appear wrong action. Interference is a headache in a live environment. In the design of the system, the intermediate links should be reduced as far as possible, and the motor motion curve should be realized by using the programming function in the driver, so as to reduce the interference caused by external pulse in the transmission process. (3) In order to make the positioning of the equipment more accurate, it is necessary to make
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Material characteristics of blister packaging Pharmaceutical blister packaging includes pharmaceutical aluminum foil, PVC plastic hard sheet, heat sealing coating and other materials. Pharmaceutical aluminum foil is a sealing material sealed on a plastic hard sheet, with the advantages of non-toxic, corrosion resistance, impermeability, heat resistance, moisture resistance, light resistance, high temperature sterilization and so on. The thickness of medicinal aluminum foil is generally 0.02mm, which is composed of a protective layer, an ink printing layer, a substrate and an adhesive layer. Because of the high cost, the all-aluminum bubble cap is mainly used for some expensive drug packaging. Pharmaceutical packaging is a very special commodity packaging which belongs to the field of packaging. It should have a variety of excellent properties of packaging; It must also have the function of maintaining the efficacy of the drug. The use of aluminum foil as a drug packaging, with beauti
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Testing requirements for blister packaging The main packaging object of blister packaging is solid drugs. The packaging should isolate the drug preparations contained in the packaging from the outside world, so as to prevent the volatile, escape and leakage of the active ingredients of the drug on the one hand. Volatile pharmaceutical ingredients can be dissolved in the inner side of the packaging material and spread to the other side under the action of osmotic pressure, such as solid pharmaceutical preparations containing aromatic ingredients and endogenous volatile active ingredients, whose active ingredients are volatile and penetrate some materials. On the other hand, it can prevent the outside air, moisture, foreign matter and microorganisms from entering and contacting with the drug. The air contains oxygen, water, a large number of microorganisms and foreign matter particles, these components into the packaging will lead to oxidation, hydrolysis, degradation, contamination and
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Material requirements of blister packing machine The packaging of medicine must meet the requirements of moistureproof, mildew proof, frost proof, heat proof and light proof. Metal aluminum non-toxic tasteless, has excellent shading sex, moisture resistance, resistance capability and taste, perfect foil to completely cut off any gas and light, can be the most effective protection by packaging, almost all the requirements not pervious to light and high barrier material, adopt aluminum foil as the barrier layer, so the aluminum foil is widely used in medicine packing industry, It is often used as an inner packaging material in direct contact with the drug. At present, compared with imported products, there is still a gap in the quality of aluminum foil application in China, mainly manifested in the following aspects: One is the number of pinholes in the medical aluminum box can not reach the use requirements. The number of pinholes in aluminum foil is a penetration defect, which seriou
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Blister packing machine heating plate station problem (1) the forming of the PVC into bent, appear this kind of situation is often in the sealing station bubble, this problem occurs because the heating plate and the forming die is not parallel, uneven heating, causing big deformation of the heated to form a bent, appear this kind of circumstance needs to forming dies as a benchmark to leveling up and down heating plate; (2) The forming PVC bubble holes in the inner and outer sides of the mold are always not full. This phenomenon may be caused by gaps in the heating plate and instability in the temperature of the heating plate! Therefore, there is no gap in the heating period during the operation of the heating plate. (3) The air bubbles in the middle of the mold are not full, because the PVC is flexible after heating, and the PVC that is not held up in the operation process is naturally sagging under the influence of gravity. The middle PVC may be stuck on the cooling mold, leading