Problems that are easy to occur in capsule filling Loading difference. The main reasons are capsule factor, drug factor, filling equipment factor and so on. If filling is required, the fluidity of the drug can be improved by adding appropriate excipients or particle preparation methods. The filling equipment must be repaired and maintained in a timely manner to ensure its normal operation. Moisture absorption. This is the most common problem in the preparation of capsule filling, because after water absorption, the contents of the capsule will become soft, dense and even moist, while after water absorption, the capsule will become soft and deformed, affecting the quality and efficacy of drugs. The solutions are as follows: on the one hand, strictly control the ambient temperature and humidity during the storage of empty capsules, and treat and fill the materials; On the other hand, improve the preparation process (such as granulation, waterproof coating, etc.), and then adopt moi

Blister packaging machine use process adjustment First of all, adjust the forming box body, adjust the synchronization of forming, hot sealing and punching. Loosen the lock nut at the bottom of the box, turn the handwheel to make the box move horizontally, adjust the box to the desired position, and tighten the nut. Adjust the forming mold to align with the guide rail, keep the level, and make THE PVC pull through the guide rail. Adjust the upper mold, adjust the PVC position, adjust the alignment of the upper and lower molds, loosen the circular surface of the nut and the upper plate to separate completely, tighten the four nuts respectively to make the upper and lower molds completely match, and then rotate the nut to the bottom of the forming fixing plate. Adjust the lower heat sealing box, loosen the lock nut on the base, turn the handwheel, make the lower heat sealing box move horizontally according to the instruction of the staff, adjust the heat sealing position, and

Weight adjustment of tablet for tablet press During the stamping process, the weight difference of the tablets tends to increase. What should be done? (1) Punch length is not uniform: the workpiece weight difference may increase, so calipers should be used to check whether each punch is qualified. If individual reductions may be due to failed discharge movements and low particle fill volumes, individual reductions should be checked well to remove obstacles. (2) the hopper level unit is wrong: may result in a hopper particles falling rapidly, the particles on the feeder, another hopper slow accumulation of particles, the particles on the feeder, less lead to imbalance, joining the two particles hopper production, hopper position is adjustable, must maintain a certain number of particles and lose speed, the accumulation of two hopper about the number of particles, particles can join hole. (3) Feeding hopper blockage: in the buffer zone of the tablet, if the particles are stic

Matters needing attention in the use of aluminum-plastic blister packing machine Batch record and equipment operation record should be completed in time during operation; Pay attention to formation, hot sealing site, pay attention to scald; Do not use foreign bodies or reach out your hand in the active area to avoid accidents. Regularly check cable connections to avoid friction with other moving parts, damage to wires, resulting in short circuits and leakage of electricity; The pressure of forming, heat sealing, indentation and other parts should not be too large, so as not to affect the service life of the packaging machinery; At the beginning of operation, the preheating temperature of each heating element can be adjusted. After stable operation, the temperature of each preheating element can be adjusted to ensure the protection function of the heating element. Keep the packaging machine clean and beautiful, not be torn by hard objects or hit the stainless steel surface; Sundri

The influencing factors of the structure of the capsule filling machine The influences of the loading amount of the capsule filling machine are generally the preset position of the filling rod, the filling material, the loose density of the material and the pressure of the filling rod. General measuring tray has six station filling hole and the corresponding filling bar, with five bar filling powder compaction, there is a station filling bar within the measuring cylinder pressure into the hole of the powder capsule, the five station filling bar preset position determines the pressure into the powder weight measuring hole and thus into the filling bar preset position. Due to the difference of the smoothness, particle form and state of the material itself, the amount of the capsule is also different under the same measuring hole, preset depth of the filling rod and the pressure of the filling rod. The state of the material can be adjusted according to the previous experience, and some

The role of a single stamping machine Single stamping machine presses all kinds of powder particles into flake, suitable for laboratory experiment production or a small amount of production of various tablets, sugar tablets, calcium tablets, heterogeneous tablets. This is a small (manual) electric continuous press with one set of stamping dies, adjustable filling depth and thickness. We can supply all kinds of moulds according to customer's requirement. The simple tablet press is suitable for chewing tablets, traditional Chinese medicine tablets, foaming agent, button battery, western medicine, electronic components, calcium tablets, chemical fertilizer tablets, oral liquid, mothballs (ball), milk tablets, candy, special-shape tablets, disinfection tablets, aromatic essence tablets, catalysts, pesticides tablets, ceramic powder, etc. The machine can press granular raw materials into sheets, the products are widely used in pharmaceutical, chemical plants, hospitals, scientific

Blister packing machine blow molding Blister packaging machine blow molding is a kind of plastic processing, its main principle is the plastic film after heating soft, vacuum attached to the mold surface, cooling molding, widely used in plastic packaging, lighting, medicine and other industries. Blister packaging products mainly include: flat blow molding box, also known as vacuum chamber, blow molding packaging equipment, pressure blow molding machine, etc. The rigid transparent plastic sheet is transformed into a specific concave plastic by the blow molding process and placed on the surface of the product for protection and beautification. The surface of the ordinary hard plastic film and a layer of soluble material are bonded together to make the surface of the tray soluble, so as to improve the quality of packaging. Mold production blow plaster mold, the cost is lower, followed by galvanized copper template, the more expensive is aluminum template. We often talk about blow mo

Filling accuracy of capsule filling machine At present, most of the domestic capsule filling machines are standard models of quantitative filling. The filling volume is determined by the thickness of the measuring plate and depends on the free density of the filling material. At the same time, the accuracy of filling quantity control is related to the influencing factors of filling structure and filling material itself. The hygroscopicity of the filling material is a factor affecting the control accuracy. When the filling powder or particle viscosity is too high and the fluidity is poor, the viscosity will produce plug powder. Usually, during the process of the mixed filling of any drug powder or particle, the humidity will be controlled below 3%. In addition, the moisture absorption capacity of the filler is related to its critical relative humidity. Generally speaking, when the purity of filling powder or particle is not high, its critical relative humidity decreases and multi-

The tablet quality of the tablet press In addition to particle quality, production environment and operator proficiency, tablet quality is closely related to the state of the machine. Therefore, it is important to keep the machine in good working condition. The following provisions shall be observed: Before starting the operation, the staff shall ensure good lubrication according to the lubrication mark, lubrication position and oil amount specified in the lubrication chart and the fuselage manual. Strictly implement SOP operation of equipment. After the end of the daily work, wipe the powder remaining in each part of the machine clean and clean the machine carefully. When the mold is disassembled or installed, be careful not to impact the mold to avoid defects. Regular inspection of worm, worm and other components, found defects timely repair or replacement. Computer controlled tablet presses should be shut down in strict accordance with the shutdown procedure to

The foreground market of blister packing machine According to the latest information released by the foreign marketing Organization on the European pharmaceutical packaging market, the focus of manufacturers on active pharmaceutical packaging is likely to change significantly over the next few years, particularly with a shift to blister packaging and carton packaging. Therefore, in the next five years, packaging materials, production equipment and other aspects in China's pharmaceutical industry still need to further accelerate the development of pharmaceutical blister packaging to further strengthen the quality and service quality of Chinese pharmaceutical packaging. Adequate and effective protection of medicines. Like any form of packaging to protect a drug, ensuring the effectiveness of the drug remains the basic requirement of blister packaging. Safe and convenient to use. Develop safe packaging and packaging suitable for children to facilitate the elderly. Unique secur