The tablet problem of the tablet press It is very common for pills to have black spots and other colored spots. According to the specific situation, the choice of pills is certain. So how can we find out the reason? If it's a black spot, it could be a carbonized raw material, or it could be a loose handle on the ring. If the color is different, then it is necessary to check the different parts of the tablet press, rule out different possibilities. Missing edge is also a common problem in tablets. It is mainly caused by the collision of the tablet's sieving machine or jinjian machine, but it may also be damaged by the punch. Lobes generally need to adjust the pressure of the press, speed, etc., generally can pass, if there is no need to pour, to see whether the funnel is blocked. For loose pieces, also want to adjust the pre - pressure, rotation of the main pressure, and then may be the cause of the particles, such as the particles are too dry, humidity is too small, viscidi

Common problems in operation of blister packaging machine Some advanced aluminum-plastic blister packaging machines are equipped with various automatic control devices, which can perform various protection functions and automatically stop operation when the following situations are detected: Detection that the protection screen is open; Insufficient compressed air pressure; The heating temperature does not reach the required temperature; Lack of PVC film or aluminum foil material; The packaging products are exhausted; Mechanical overload in some workplaces; Circuit overload. The machine will not start until the following problems are resolved: The protective cover is completely closed; Compressed air pressure is sufficient; The heating temperature reaches the required temperature; PVC or aluminum foil material is normally installed; No load or other resolved fault; Function key configuration is correct, emergency stop key reset, etc.

Classification of capsules Capsule is divided into soft capsule and hard capsule commonly, hard capsule has gelatin capsule and plant capsule again cent. The hard capsule is composed of two exquisitely processed capsule shells. Capsules come in different sizes, including capsule Numbers 000#, 00#, 0# -5 #. The printed text can also be coloured on the capsule to give a unique and personal feel. One part of the capsule body has a tapered edge, allowing the capsule to be gently encapsulated in a high-speed filling machine. Double closed loop system can make the capsule sealed before filling and completely sealed after filling. The capsule is also designed to include permeable holes to prevent unnecessary air pressure entering the capsule during the high-speed filling process, resulting in a reaction. Plant capsule is a hollow capsule made of plant cellulose or water-soluble polysaccharide to meet the needs of preparation and localization of the capsule. It retains all the a

The heat seal form of blister packing machine The bubble wrap machine fills the bubble shell with the drug, the heat seal film covers the drug, and then the two seal. The basic principle is that the inner surface is heated and pressurized so that it is in close contact, forming a complete welding table in a short time. There are two types of heat sealing: roller type and plate type. (1) Roller type. Sealing material is continuously rotating through two rollers, and sealing packaging material is continuously rotating through two rollers and the pressure residence time is very short, hot sealing requirements, the occurrence of a certain speed is too slow or packaging material must be fully preheated coil before proceeding. (2) Pressure equation. The sealing material shall be a seal arriving at the terminal, touching the sealing surface by the heated sealing hot plate and the underlying formwork, subject to pressure welding together, and quickly leaving to complete a periodic pac

The use of tablet press 1. Before use, it is necessary to repeatedly check the die quality of the tablet press for lack of edges, cracks, deformation, insufficient compaction, etc., and check whether the equipment is complete and operates normally. 2. Check whether the dust in the granule raw materials is dry and whether the dust content in the granule does not exceed 10%. Otherwise, it will affect the normal operation and service life of the tablet press, and affect the loss of raw materials. 3, the first machine is a dish of pressure regulator control instruction to 6, pour the powder into the feeder, test wheel, hand and drug regulation at the same time, inflation pressure to increase the weight, hard and soft finished product, and then start the engine, open the clutch and the formal production operations, in the process of production, should check the quality of drugs, if not qualified, need to make the necessary adjustments. 4. The choice of speed directly affects the

Maintenance of capsule filling machine 1. When the machine runs normally for a long time, when a batch of drugs is changed or shut down for a long time, the parts in direct contact with the drugs should be cleaned regularly. 2. The transmission mechanism under the working platform of the machine tool should be constantly added with appropriate lubricant to reduce the wear of parts. 3. The main transmission reducer should be checked once a month to see if the oil is insufficient, and it should be replenished timely. The oil should be changed every 6 months; Change the oil every 3000 hours. Oil should be used as a rule of thumb. 4.Safety protection clutch, normal load overload clutch does not slip, but due to long-term use may appear slip phenomenon, when the clutch sliding phenomenon, may be the screw nut to tighten, to ensure the normal operation of the machine. 5. The vacuum system of the vacuum separator in the filling capsule is mainly used to put the cover on the body after

Classification of tablets Ordinary tablet: A tablet mixed with an excipient, usually taken with water. Capsule: A piece used to line the cardiac membrane. The purpose of coating is to improve the stability of the drug in the tablet, cover up the odor of the drug, improve the appearance of the tablet and so on. Sugar-coated tablets refer to tablets made from sugar-coated materials. The coated film refers to the flake of subcontracted polymer film; Enteric-coated tablets refer to the insoluble gastric juice which is outsourced, but the soluble long-leaf tablets are used to prevent gastric juice damage and gastric irritation. Multilayer tablet: Tablet consisting of two or more layers (different ingredients, formulations, or colors) to improve appearance or regulate duration of action, or to reduce exposure to two layers of medication, or to reduce changes in compatibility, etc. Tablets may be divided into two or more layers from top to bottom, or several layers, concentr

Classification of capsules Capsules are generally divided into hard capsules, soft capsules (capsules), sustained-release capsules, controlled-release capsules, enteric-coated capsules, etc. 1. Hard capsules (capsules): gelatin capsules, such as uniform powder, particles, tablets, tablets, semi-solid or liquid, mixed by drugs or excipients and appropriate excipients, shall be filled into the hollow capsules according to the appropriate preparation process. 2. Soft capsule: refers to the capsule made by directly dissolving or dispersing a certain amount of liquid drug capsule, or dissolving or dispersing solid drug in appropriate auxiliary agent, or dissolving in solution, suspension, emulsion or semi-solid, and sealing it in the soft capsule material. Soft capsules, also known as gelatin capsules, can be prepared by drip irrigation or extrusion. 3. Sustained-release capsules: the capsules that release drugs slowly but not constantly in the prescribed sustained-release mediu

The structure and composition of blister packing machine Pharmaceutical blister packaging machine production, there may be many forms, in a different way to complete the packaging operations, but the basic functional components and composition is same, mainly by the material volume, heating, forming, filling, heat sealing, batch number, blanking, power transmission system, and the air pressure, cooling, control and frequency control system, etc. 1. Material release coil: plastic film and aluminum foil coil are fixed on the equipment, equipped with pressure device, brake and axial position adjustment device, and also equipped with cursor tracking device. 2. Heating part: the rigid sheet of plastic film softened by electric heating is adopted. 3. Forming part: forming plate, connecting plate, vacuum system (compressed air), cooling water system, etc. 4. Filling part: The feeder fills tablets, capsules, etc. into the formed bubbles. 5. Heat sealing part: it is composed o

Press die for sheet pressing machine There are many forms of press die, but we can distinguish them by the equipment, materials, standards and forms used: According to the equipment used, there are single stamping die, rotary stamping die and flower basket stamping die. According to the materials produced, there are alloy steel punching die, carbon punching die, ceramic punching die, chromium punching die, titanium punching die; The most commonly used alloy steel materials for commercial presses are :GCr15, Crl2MoV, 9Mn2V, 9CrSi, etc. The most commonly used materials for imported punching die are :A2, O1, S1, PHG-P, etc. According to the standard, there are ZP standard, IPT international standard, European Union standard, and a variety of non-standard die, battery ring die. Single stamping die varies from model to model and style. According to the specification, diameter and shape of the tablet, the mold of the single chip microcomputer and rotary tablet press can be divided into